Macromolecule Lesson Plans

        Biomolecules, organic compounds & molecular biology lesson plans designed for high school and middle school science teachers are downloadable here. A great biochemistry experiment is where students use common household acids and bases to test for pH. A dehydration synthesis activity lets students combine paper molecules and form water. Biochemistry projects include researching different proteins, their amino acid structure, and their functions. Molecular biology worksheets and exam / test / quiz questions also provide help with evaluating the student’s progress. NGSS Life Science offers many great lessons. Click the titles below to see a list of lessons for each category. Free macromolecule lesson plans include:
  • Proteins Lesson Plans

    • Polypeptides - 20 different amino acids, peptide bonds.
    • Amino Acids - amino group, carboxyl group, side R groups.
    • Shape - folding chains of amino acids, hydrogen bonds, shape determines function, primary, secondary, plated sheet, alpha helix, tertiary, quaternary structures.
    • Functions - enzymes, structure, movement, energy source, transport, immunity.
    • Food Types - dairy, eggs, fish, grains, legumes, meat, nuts, poultry, seeds, vegetables.
  • Carbohydrate Lesson Plans

    • Carbohydrates - monosaccharides, disaccharides, polysaccharides.
    • Monosaccharides - glucose sugar, fructose.
    • Disaccharides - sucrose sugar, lactose, maltose.
    • Polysaccharides - starch, glycogen, cellulose.
    • Food Types - sugar, breads, cereal, fruits, milk, pasta, vegetables.
    • Fiber Types - apple, baked potato, barley, bran cereal, dried beans, pear.
  • Lipid Lesson Plans

    • Lipids - fats, lipoproteins, phospholipids, sterols, triglycerides.
    • Lipoproteins - VLDL very low density lipoprotein, LDL low density lipoprotein, HDL high density lipoprotein.
    • Phospholipids - lipid bilayer, 2 fatty acid tails, one glycerol, one phosphorus acid chain.
    • Sterols - steroids, cholesterol.
    • Triglycerides - saturated fatty acids, unsaturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, trans-fatty acids.
    • Food Types - butter, cheese, meats, milk, nuts, oils.
    • Saturated Fat Types - butter, coconut oil, lard, palm oil.
    • Unsaturated Fat Types - avocados, Canola oil, fish, olive oil, sunflower oil.
    • Cholesterol Types - eggs, dairy, fish, meats, poultry.
  • Nucleic Acids Lesson Plans

    • Polymers - DNA, RNA.
    • Nucleotides - hydrogen bonds, phosphate group, deoxyribose and ribose pentose sugars, nitrogen bases.
    • Structure - double helix, mRNA, tRNA, rRNA.
  • Acids and Bases Experiments

    • pH - common acids and bases.
    • Acids - acidic solutions, common acids, hydrogen ions.
    • Bases - alkaline solutions, common bases, hydroxide ions.
    • Buffers - weak acid or base with its conjugate base or acid, keep pH constant.
  • Biochemistry Basics Lesson Plans

    • Organic molecules - monomers and polymers of macromolecules
    • Inorganic molecules - water , carbon dioxide
    • Dehydration synthesis - loss of an H2O molecule, making of polymers.
    • Hydrolysis - addition of an H2O molecule, splitting of polymers into monomers.
    • Atoms - protons, neutrons, electrons, orbital shells.
    • Elements - periodic table, carbon, hydrogen, oxygen, nitrogen.
    • Compounds - chemical bonds.
    • Covalent Bonding - sharing of electrons.
    • Ionic Bonding - gaining or losing electrons to form ions.
    • H2O - hydrogen bonds, polarity of water, cohesion, adhesion.
Amino Acid

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Free Lesson Plans

NGSS Life Science is a curriculum community for middle school and high school science teachers. High school and middle school curriculums include carbohydrate experiments, protein labs, macromolecule projects, dehydration synthesis activities, pH demos, acid and base worksheets, and biochemistry exam / test / quiz questions. Some lesson plan topics include macromolecules, carbohydrates, proteins, lipids, nucleic acids, water molecules, acids and bases, and more.